SHP2 is essential for the progesterone-promoted proliferation and migration in breast cancer cell lines
IntroductionWe previously demonstrated that progesterone (P4) can promote breast cancer cell proliferation and migration through activating the P4 receptor (PR)/cSrc-mediated signaling pathway.It has been suggested that high level of Src homology region 2 domain-containing phosphatase-2 (SHP2) might be involved in breast oncogenesis.This study aime